Healthspan Program KHARIS
strategies for aging gracefully
![Family Lunch](https://static.wixstatic.com/media/11062b_2264e8113c5743b89824e233c8f226cb~mv2.jpg/v1/fill/w_1056,h_694,al_c,q_85,usm_0.66_1.00_0.01,enc_avif,quality_auto/11062b_2264e8113c5743b89824e233c8f226cb~mv2.jpg)
KHARIS ("Grace" in Greek) mission is to develop new strategies that improve healthspan, which leads to improved quality of life, and reduce healthcare spending.
​KHARIS is using systems and genetics approaches to understand the aging process. The research of Pr. Johan Auwerx spurred the development of new drugs, for the treatment of non-communicable diseases of the metabolic, cardiovascular, renal, and neuro-muscular systems. ​
​
KHARIS‘ mission is to:
​
-
define personalized healthspan metrics and trajectories by integration of mouse and human data
-
map predictive and causal factors of the decline of health, loss in resilience, and age-related disease
-
identify and validate candidate healthspan and disease targets
-
develop modality-agnostic strategies/therapeutics to increase healthspan and resilience
-
create a digital twin of health to facilitate silicon clinical trial
The Kharis Engine
Three modules enable integrated TIDVAL and translation
![d290dfdb-3bb3-427b-a06c-d36aeb6c67ea.webp](https://static.wixstatic.com/media/616b56_4e2585f70d16436c94c2baa3e49232ca~mv2.webp/v1/fill/w_741,h_589,al_c,q_85,usm_0.66_1.00_0.01,enc_avif,quality_auto/d290dfdb-3bb3-427b-a06c-d36aeb6c67ea.webp)
![f6297570-9f40-4420-80e3-5d71686eb8e5.webp](https://static.wixstatic.com/media/616b56_da4e283259684d21bb2cc6dca24a6a1a~mv2.webp/v1/fill/w_570,h_538,al_c,q_80,usm_0.66_1.00_0.01,enc_avif,quality_auto/f6297570-9f40-4420-80e3-5d71686eb8e5.webp)